The Illustrated Dictionary of Toxicologic Pathology and

  • Hardcover
  • 672 pages
  • The Illustrated Dictionary of Toxicologic Pathology and Safety Science
  • Pritam S Sahota
  • 12 May 2016
  • 9781498754712

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The Illustrated Dictionary of Toxicologic Pathology and Safety Science There has been a growing interest in toxicologic pathology especially as related to its impact on the safety assessment of pharmaceuticals and chemicals and in drug development Thus there is a growing need for an Illustrated Dictionary of Toxicology Pathology and Safety Science IDTP that this dictionary aims to fill The language of toxicologic pathology may be less familiar to a broad range of safety scientists especially those involved in the safety evaluation of pharmaceuticals and chemicals The IDTP format provides the brevity and clarity that the user is not likely to receive in a textbook even if adeuately indexed With the inclusion of descriptions for terms used in toxicology drug metabolismpharmacokinetics and regulatory science the scope of the IDTP is considerably broadened and decidedly uniue in its appeal to all safety scientistsWith over 800 photos and illustrations to provide visual context an important aim of the IDTP is to present pathological changes as reference examples for terminology nomenclature and term descriptions for the entry entry level as well as seasoned toxicologic pathologist It will also aid students and non pathology specialists such as study directors senior toxicology report reviewers scientific management of contract research organizations regulatory agencies and drug development companies to better understand the biological significance of tissue changes The IDTP provides a single reference volume for these users to further their understanding and appreciation of biologically significant pathology findingsThe IDTP consists of four major areas1 A Z Dictionary of Pathology encompassing all organ systems together with relevant non pathology terms supported by references in For Further Reading sections2 Appendix 1 An Overviews of Drug Development Nonclinical Safety Toxicologic Pathology and ImportantSpecial Topics3 Appendix 2 Diagnostic Criteria of for Proliferative Proliferative Lesions in Rodents Rat and Mouse and Selected Non Rodent Laboratory Species containing illustrations with detailed references and links to source material4 Appendix 3 Mini Atlas of Organ System Anatomy and Histology to help re acuaint the non pathologist safety scientist with many normal anatomical structures The editors and contributing scientists board certified veterinary pathologists board certified toxicologists allied health safety scientists health regulatory representatives have experience from bench level pathology and toxicology to managing global preclinical safety units in leading pharmaceutical companies They have considerable experience mentoring pharmaceutical industry project team members interacting with industry clinicians and representatives of decision making bodies within the industry as well as with global health authorities such as the FDA and EMA These activities convinced them of the necessity for and usefulness of the IDTP As experts in their field they have undertaken the hard work of writing and compiling the information making the IDTP an exceptional go to referenceIllustrations Editor Gregory Argentieri